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FIGURE 9 Discussion Glutathione peroxidase is a crucial antioxidant enzyme that participate in restraining the harmful accumulation of intracellular hydrogen peroxide and is more effective than catalase at eliminating intracellular peroxides under various physiological conditions ( In the present study, the role of GPX1 in SGNs treated with peroxynitrite was explored via using ebselen and GPX1 deficient mice