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Consequently, the inhibition of TNF-α attenuates inflammatory reactions and allows anti-inflammatory signaling pathways to prevail again, giving the chance for a restoration of the homeostatic immunological balance [13,14,16,29,30,45]
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Collagen synthesis: GHK-Cu activates matrix metalloproteinase inhibitors (TIMPs) while also activating MMP-2 and MMP-9 at specific concentrations, producing a net effect of organized matrix remodeling rather than simple collagen deposition