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I've not come across the negative side effects you list

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DOAC in Treatment of Blood Clots & Thrombosis and repurposing colchicine in Novel & Emerging Strategies to Prevent & Treat Thrombosis 2025 Nov : Updated section on nattokinase in Nutrients 2024 Jun : Updated section on direct oral anticoagulants (DOACs) in Treatment of Blood Clots & Thrombosis 2021 Nov : Comprehensive update & review Disclaimer and Safety Information This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional