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In AR12, MS has been more specifically defined as relapsing remitting MS, i.e., RRMS: Furthermore, defendants assert insufficiency of disclosure, invalidity of the priority claim, lack of novelty over WO 2006/037342, and obviousness in view of: KAPPOS et al

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This compound has been widely referenced in preclinical research exploring cellular signaling pathways, tissue interaction models, and peptide stability studies