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It is a copper-binding tripeptide that has been studied for collagen and elastin synthesis, the proteins that give skin its firmness and connective tissue its strength

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Moreover, although the surface of HGF II-K1 for c-MET binding is exposed, the binding of another c-MET to HGF II-K1 in such rigid conformation would clash with HGF I bound c-MET II on the stalk region, explaining why rigid HGF II in the 2:2 complex cannot recruit additional c-MET molecule