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Even when ingested in normal amounts, copper and iron may become toxic in certain individuals with genetic predispositions that lead to hepatic overload - iron overload in hemochromatosis [11-17] or copper overload in Wilson disease [18-27]

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DSIP-associated experimental research provides a framework for examining relationships among peptide signaling, hypothalamic-pituitary-associated processes, stress-response signaling, and downstream endocrine pathways