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The Rest of the Pipeline Isn’t Standing Still Retatrutide and CagriSema get most of the attention, but at least six other Phase 3 programs are active in 2026, and each is worth knowing by name: Orforglipron already crossed the finish line — FDA approved in April 2026 under the brand name Foundayo, the first small-molecule, non-peptide oral GLP-1 agonist

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The hypothalamus influences hunger signaling and energy balance